内镜下黏膜剥离术护理体会

内镜下黏膜剥离术（Endoscopic submucosal dissection，ESD）是内镜下黏膜切除术（Endoscop—icmucosal resection，EMR）基础上发展而来的新技术，主要针对大而平坦的黏膜早期癌变或黏膜下的病变，进行一次性大块剥离，不但能整体切除病变，还可以进行完整的病理学检查。     

乳果糖口服液对肝硬化患者肝功能和肠黏膜屏障功能的影响分析

目的探讨和分析乳果糖口服液对肝硬化患者肝功能和肠黏膜屏障功能的影响。方法将我院84例肝硬化患者随机分为对照组和观察组,对照组给予呋塞米注射液、甘草酸二胺注射液治疗,观察组患者在此基础上给予口服乳果糖口服液,观察对比治疗前后2组患者肝功能和肠黏膜屏障功能的变化情况。结果治疗后,2组患者的ALT、AST、TB、血清内毒素、D-乳酸、PCT水平较治疗前均明显改善(P0.01),且观察组治疗后的肝功能和肠黏膜屏障功能各项指标均明显优于对照组(P0.01)。结论乳果糖可改善肝功能和肠黏膜屏障功能的各项指标,阻止肝硬化病情恶化,提高患者生活质量。     

The importance of temperature on the neurovascular unit

Therapeutic hypothermia is the only treatment that has been shown to be of benefit to infant's ≥ 36 weeks of gestation with hypoxic–ischemic encephalopathy. The evidence for the benefit is based on multiple, well-designed randomized clinical trials. Based on this data, the use of therapeutic hypothermia has been widely disseminated throughout the neonatal community. An important concept in hypoxic–ischemic brain injury is the functioning of the neurovascular unit which links neurons, non-neuronal cellular elements and the capillary endothelial cells to promote optimal barrier maintenance between the brain and systemic circulation, regulation of blood flow and neuro-immunologic functioning. Hypoxic–ischemic injury can trigger increased permeability of the blood‐brain-barrier via molecular events within the neurovascular unit and initiate pathways to brain injury. In addition, exposure of the brain to cellular elements from the systemic circulation can further propagate the neuro-inflammatory response. The influence of temperature on injury to the neurovascular unit has received relatively little attention. This review will focus on one component of the neurovascular unit, the blood‐brain barrier and its constituents. Specifically, this review will address the effects of hypoxia–ischemia and temperature on the neurovascular unit and potential knowledge gaps which may serve as areas for further investigation.     

Histocytological study of the guided bone regeneration using the rat mandible

Histological changes, localization of osteoblasts, and activating time at defective areas of rat mandible were studied with the GBR technique using absorptive (dura mater) and non-absorptive (GTAM) barrier membrane. We examined the rat-mandibles which had been operated by the GBR technique and obtained following results: